Associate Director, Preclinical Research
Gaithersburg, MD
We’re hiring a hands-on Associate Director of Preclinical Research to manage a small team while contributing directly to lab work and advancing preclinical programs. This role is responsible for overseeing lab operations, partnering cross-functionally and with CROs, and helping translate research into clinical strategy.
About Remedy Plan Therapeutics
Remedy Plan Therapeutics is a clinical-stage biotech company focused on developing NAMPT inhibitors for patients with acute leukemias and solid tumors. Our mission is to solve a decades-old medical-science puzzle: targeting NAD synthesis in cancer cells without damaging healthy cells. Our lead asset, RPT1G, is a novel, small-molecule NAMPT inhibitor designed for this purpose. Our team comprises experienced scientists, clinicians, and drug developers working together to bring hope to communities affected by these diseases. For more information on Remedy Plan, visit remedyplan.com and follow us on LinkedIn.
Description
Key responsibilities
Manage a small team of R&D scientists with a focus on career development and departmental excellence, including experimental execution and optimization
Contribute directly to laboratory work and experiments (expect up to 40% hands-on lab work)
Oversee daily lab operations, organization, and safety
Design and execute mechanistic and efficacy studies in relevant disease models with CROs
Help develop preclinical-to-clinical rationale including dose/schedule justification and biomarker strategy
Contribute to IND-enabling study design and execution, including managing non-GLP and GLP toxicology programs at CROs
Collaborate cross-functionally with Translational, Clinical Operations, CMC, Regulatory, and Business Development teams
Interface with and support academic collaborators and advisors
Present data internally and externally; contribute to publications, conference abstracts, and grant applications, may involve up to 10% travel for conferences or other meetings
This role reports directly to the CSO and will collaborate closely with the Director, Translation Sciences, COO, and Director, Clinical Operations
Qualifications
Required
Ph.D. in biochemistry, cancer biology, or a closely related discipline
5+ years of industry experience in drug development or a related field
Experience with direct management of R&D scientists
Hands-on expertise in cancer cell biology and in vivo pharmacology, including PK/PD study design and interpretation
Proficiency with bioinformatics analysis (RNAseq, genomics, metabolomics, proteomics) and comfort handling and visualizing complex multi-modal datasets
Experience supporting or leading IND-enabling programs, including CRO management and regulatory data package preparation
Demonstrated ability to operate independently, prioritize effectively, and drive programs forward in a resource-constrained environment
Desire to work in a fast-paced and exciting startup environment
Preferred
Expertise in cancer metabolism
Experience with translational biomarker development
Prior experience in a startup or early-stage biotech; comfort wearing multiple hats